Abstract:

Nowdays, the relevance of higher education in the 21st century in terms of the need to adapt and respond to new modes of knowledge production is highlighted [1].
Learning outcomes are statements of what a student is expected to know, understand and/or be able to demonstrate after completion of a process of learning [2].
The traditional teaching is commonly referred to as a teacher-centred approach. A criticism of this one is the difficulty in stating precisely the actual student’s skills after passing a module or programme. Therefore, international trends in education show a shift from the “teacher-centred” approach to a “student-centred” approach [2].
Morover, for industry, a new mode of knowledge which is produced in the context of application is important [1].
At this moment our research projects are focused on the use of Molecularly Imprinted Polymers (MIPs) as synthetic recognition elements, considering their promising applications [3]. So, the purpose of this paper is to report our multimodal experience of teaching, learning and reseach, developing a practical guide to learn first MIPs concepts from reseach articles.
PRACTICAL GUIDE DETAILS.
1.- CONCEPT AND POLYMERIZATION PROCESS.
- According to the following reports, select the key words that explain MIPs concept. Documents: Macromolecules 2002, 35, 79-91; Anal. Chim. Acta 504 (2004) 131–135; Anal. Chim. Acta 542 (2005) 118–124; Biosens. Bioelectron. 25 (2009), 553-557.
- Propose a figure or scheme to explain the principle of MIPs tecnology.
Documents: Trends Biotechnol. 16 (1998) 468- 475; Chem. Rev. 100 (2000) 2495-2504; Methods 22 (2000) 92-106; Prog. Polym. Sci. 33 (2008) 271–288; J. Mol. Recognit. 19 (2006) 106-180.
- Using the information reported in Box 1 of the paper, Trends Biotechnol. 16 (1998) 468- 475, list elements for the reaction mixture, types of initiation methods, type of polymerization to prepare uniform spherical polymer beads directly, solvent used for extraction step.
- List the main physical factors that affect the polymerization process, underlining the most important to control performance of MIPs.
Document: Macromolecules 42 (2009) 4921–4928
2.- SYNTHESIS EVALUATION. Identify the different steps in the rebinding procedure used in a batch rebinding method to evaluate the synthesis of MIPs.
What is the significance of Imprinting Factor? What is it used for? How the value of Imprinting Factor is obtained?
What is the significance of Selectivity? What is it used for? How the value of Selectivity is obtained?
Documents: Adv. Drug Deliv. Rev. 57 (2005) 1779–1794; Macromolecules, 30 (1997) 1317-1322.
3.- CHARACTERIZATION MIPS. What are direct physical characterization methods for MIPs?
Document: Adv. Drug Deliv. Rev. 57 (2005) 1779–1794.
4.- APPLICATIONS. List the main applications of MIPs
Documents: Chem. Rev. 100 (2000) 2495-2504; Anal. Chem. 75 (2003) 376 A-383 A; Anal. Bioanal. Chem. 378 (2004) 1331–1337; Biosens. Bioelectron. 25 (2009) 553-557.
References.
[1] P. O. Iyuke; M. Cross; S. E. Iyuke; H. J. Potgieter. Educ.Chem. Eng. 2 (2007) 56–67
[2] J.J. Fitzpatricka; E.P. Byrnea; D. Kennedy. Educ.Chem.Eng. 4 (2009) 21–28
[3] Richard J. Ansell; Nicole Kirsch; Ian A. Nicholls; John O’Mahony; Michael J. Whitcombe. J. Mol. Recognit. 19 (2006) 106–180

Keywords:

Learning outcomes, reseach articles, molecularly imprinted polymer.